MSMB (Beta-microseminoprotein) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Prostate cancer.
UniProt has no function text for P08118; HGNC names it "microseminoprotein beta".
Open Targets scores its association with cancer at 0.63 (direct and indirect evidence; datatypes literature 0.93, animal model 0.30, genetic association 0.69, genetic literature 0.61).
In plain words · MSMB (Beta-microseminoprotein) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Prostate cancer.
MSMB (Beta-microseminoprotein) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Prostate cancer.
UniProt has no function text for P08118; HGNC names it "microseminoprotein beta". Location: Secreted (UniProt).
No product in this corpus aims at MSMB yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
First described 1984. Earliest sequence paper UniProt cites for the protein: Seidah N.G. et al, FEBS Lett, 1984, "Complete amino acid sequence of human seminal plasma beta-inhibin. Prediction of post Gln-Arg cleavage as a maturation site". Source.
Sources: HGNC HGNC:7372 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt P08118 (protein name, function text, keywords and locations (REST API)); Open Targets ENSG00000263639 (association with cancer (MONDO_0004992) 0.63; per-cancer scores at or above 0.5: prostate cancer 0.63 (GraphQL API, CC0))
UniProt has no function text for P08118; HGNC names it "microseminoprotein beta". Location: Secreted (UniProt). Locus 10q11.22 (HGNC).
Query for this target: (TITLE:"MSMB" OR ABSTRACT:"MSMB" OR TITLE:"microseminoprotein beta" OR ABSTRACT:"microseminoprotein beta" OR TITLE:"Beta-microseminoprotein" OR ABSTRACT:"Beta-microseminoprotein" OR TITLE:"PSP-94" OR ABSTRACT:"PSP-94" OR TITLE:"PSP57" OR ABSTRACT:"PSP57" OR TITLE:"PSP94" OR ABSTRACT:"PSP94") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about MSMB, not a curated reading list.