MIR21 (microRNA 21) is a gene. The public catalogues list it as a drug target and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Non-small-cell lung cancer.
UniProt has no function text for this gene; HGNC names it "microRNA 21".
CIViC holds 4 clinical evidence items and 0 assertions across 1 variant, naming Cisplatin.
In plain words · MIR21 (microRNA 21) is a gene. The public catalogues list it as a drug target and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Non-small-cell lung cancer.
MIR21 (microRNA 21) is a gene. The public catalogues list it as a drug target and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Non-small-cell lung cancer.
UniProt has no function text for this gene; HGNC names it "microRNA 21". Locus 17q23.1 (HGNC).
No product in this corpus aims at MIR21 yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
Specificity not established: the Human Protein Atlas has no row for MIR21 and no corpus medicine is aimed at it. Distribution: 1 cancer family in the corpus carries a prevalence row, label threshold or catalogue link for it (Lung cancer (all types)); Open Targets associates it with 0 specific cancer types at or above 0.5. (No rule of scripts/fetch-target-specificity.ts fired.)
Sources: HGNC HGNC:31586 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); CIViC gene MIR21 (4 evidence items, 0 assertions, 1 variants; diseases: Lung Non-small Cell Carcinoma, Malignant Astrocytoma, Glioma (GraphQL API, CC0))
UniProt has no function text for this gene; HGNC names it "microRNA 21". Locus 17q23.1 (HGNC).
Query for this target: (TITLE:"MIR21" OR ABSTRACT:"MIR21" OR TITLE:"microRNA 21" OR ABSTRACT:"microRNA 21" OR TITLE:"hsa-mir-21" OR ABSTRACT:"hsa-mir-21" OR TITLE:"MIR-21" OR ABSTRACT:"MIR-21" OR TITLE:"MIRN21" OR ABSTRACT:"MIRN21") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about MIR21, not a curated reading list.