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MAGEH1 (Melanoma-associated antigen H1) is a gene. The public catalogues list it as a drug target and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response.
UniProt has no function text for Q9H213; HGNC names it "MAGE family member H1".
CIViC holds 1 clinical evidence item and 0 assertions across 1 variant, naming Gemcitabine.
In plain words · MAGEH1 (Melanoma-associated antigen H1) is a gene. The public catalogues list it as a drug target and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response.
MAGEH1 (Melanoma-associated antigen H1) is a gene. The public catalogues list it as a drug target and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response.
UniProt has no function text for Q9H213; HGNC names it "MAGE family member H1". Locus Xp11.21 (HGNC).
No product in this corpus aims at MAGEH1 yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
Specificity not established: no corpus medicine is aimed at it and the catalogues give it only the roles drug-target, biomarker; HPA finds the RNA tissue enriched, which says where the protein sits but not whether the tumour differs from normal tissue. HPA MAGEH1: RNA tissue enriched (epididymis 487 nTPM); no normal tissue stained high; highest cancer staining lymphoma (6 of 12 high). Distribution: no corpus cancer carries a prevalence row, threshold or catalogue link for it; Open Targets associates it with 0 specific cancer types at or above 0.5. (No rule of scripts/fetch-target-specificity.ts fired.)
Sources: Human Protein Atlas MAGEH1 tissue; Open Targets ENSG00000187601 associations
First described 2000. Earliest sequence paper UniProt cites for the protein: Zhu et al, BioTechniques, 2000, "Improved PCR-based subtractive hybridization strategy for cloning differentially expressed genes". Source.
Sources: HGNC HGNC:24092 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt Q9H213 (protein name, function text, keywords and locations (REST API)); CIViC gene MAGEH1 (1 evidence items, 0 assertions, 1 variants; diseases: Bile Duct Adenocarcinoma (GraphQL API, CC0))
UniProt has no function text for Q9H213; HGNC names it "MAGE family member H1". Locus Xp11.21 (HGNC).
RNA: tissue enriched (epididymis 487 nTPM), detected in all normal tissues.
No normal tissue stained high.
Medium only: breast cancer, carcinoid, colorectal cancer, head and neck cancer.
Human Protein Atlas version 25.1, antibody staining at reliability approved, enhanced or supported; used under CC BY-SA 3.0. Staining counts are patients per level in the atlas cohort, not population prevalence.
Query for this target: (TITLE:"MAGEH1" OR ABSTRACT:"MAGEH1" OR TITLE:"MAGE family member H1" OR ABSTRACT:"MAGE family member H1" OR TITLE:"Melanoma-associated antigen H1" OR ABSTRACT:"Melanoma-associated antigen H1" OR TITLE:"APR1" OR ABSTRACT:"APR1") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about MAGEH1, not a curated reading list.