Loading
LSP1 (Lymphocyte-specific protein 1) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Breast cancer.
May play a role in mediating neutrophil activation and chemotaxis.
Open Targets scores its association with cancer at 0.53 (direct and indirect evidence; datatypes literature 0.95, genetic association 0.66).
In plain words · LSP1 (Lymphocyte-specific protein 1) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Breast cancer.
LSP1 (Lymphocyte-specific protein 1) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Breast cancer.
May play a role in mediating neutrophil activation and chemotaxis. Location: Cell membrane (UniProt).
No product in this corpus aims at LSP1 yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
First described 1990. Earliest sequence paper UniProt cites for the protein: Jongstra-Bilen et al, J. Immunol, 1990, "Human and mouse LSP1 genes code for highly conserved phosphoproteins". Source.
Sources: HGNC HGNC:6707 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt P33241 (protein name, function text, keywords and locations (REST API)); Open Targets ENSG00000130592 (association with cancer (MONDO_0004992) 0.53; per-cancer scores at or above 0.5: breast cancer 0.50 (GraphQL API, CC0))
May play a role in mediating neutrophil activation and chemotaxis. Location: Cell membrane (UniProt). Locus 11p15.5 (HGNC).
Query for this target: (TITLE:"LSP1" OR ABSTRACT:"LSP1" OR TITLE:"lymphocyte specific protein 1" OR ABSTRACT:"lymphocyte specific protein 1" OR TITLE:"Lymphocyte-specific protein 1" OR ABSTRACT:"Lymphocyte-specific protein 1" OR TITLE:"WP34" OR ABSTRACT:"WP34") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about LSP1, not a curated reading list.