LRATD2 (LRAT domain containing 2) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
UniProt has no function text for Q96KN1; HGNC names it "LRAT domain containing 2".
Open Targets scores its association with cancer at 0.50 (direct and indirect evidence; datatypes literature 0.91, animal model 0.32, genetic association 0.77).
In plain words · LRATD2 (LRAT domain containing 2) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
LRATD2 (LRAT domain containing 2) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
UniProt has no function text for Q96KN1; HGNC names it "LRAT domain containing 2". Locus 8q24.21 (HGNC).
No product in this corpus aims at LRATD2 yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
First described 2001. Earliest sequence paper UniProt cites for the protein: Hughes P.J. et al, 2001, "A novel NS-containing protein". Source.
Sources: HGNC HGNC:24166 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt Q96KN1 (protein name, function text, keywords and locations (REST API)); Open Targets ENSG00000168672 (association with cancer (MONDO_0004992) 0.50; (GraphQL API, CC0))
UniProt has no function text for Q96KN1; HGNC names it "LRAT domain containing 2". Locus 8q24.21 (HGNC).
Query for this target: (TITLE:"LRATD2" OR ABSTRACT:"LRATD2" OR TITLE:"LRAT domain containing 2" OR ABSTRACT:"LRAT domain containing 2" OR TITLE:"BCMP101" OR ABSTRACT:"BCMP101" OR TITLE:"NSE2" OR ABSTRACT:"NSE2" OR TITLE:"FAM84B" OR ABSTRACT:"FAM84B") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about LRATD2, not a curated reading list.