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GOLGB1 (Golgin subfamily B member 1) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
May participate in forming intercisternal cross-bridges of the Golgi complex.
Open Targets scores its association with cancer at 0.60 (direct and indirect evidence; datatypes literature 0.27, affected pathway 0.95, animal model 0.69, genetic association 0.00).
In plain words · GOLGB1 (Golgin subfamily B member 1) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
GOLGB1 (Golgin subfamily B member 1) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
May participate in forming intercisternal cross-bridges of the Golgi complex. Location: Golgi apparatus membrane (UniProt).
No product in this corpus aims at GOLGB1 yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
First described 1994. Earliest sequence paper UniProt cites for the protein: Seelig H.P. et al, J. Autoimmun, 1994, "Macrogolgin -- a new 376 kD Golgi complex outer membrane protein as target of antibodies in patients with rheumatic diseases and HIV infections". Source.
Sources: HGNC HGNC:4429 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt Q14789 (protein name, function text, keywords and locations (REST API)); Open Targets ENSG00000173230 (association with cancer (MONDO_0004992) 0.60; (GraphQL API, CC0))
May participate in forming intercisternal cross-bridges of the Golgi complex. Location: Golgi apparatus membrane (UniProt). Locus 3q13.33 (HGNC).
Query for this target: (TITLE:"GOLGB1" OR ABSTRACT:"GOLGB1" OR TITLE:"golgin B1" OR ABSTRACT:"golgin B1" OR TITLE:"Golgin subfamily B member 1" OR ABSTRACT:"Golgin subfamily B member 1" OR TITLE:"GCP372" OR ABSTRACT:"GCP372" OR TITLE:"giantin" OR ABSTRACT:"giantin" OR TITLE:"GOLIM1" OR ABSTRACT:"GOLIM1") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about GOLGB1, not a curated reading list.