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GOLGA5 (Golgin subfamily A member 5) is a gene. The public catalogues list it as a fusion partner, and the evidence so far is association rather than a proven role.
Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.
Open Targets scores its association with cancer at 0.56 (direct and indirect evidence; datatypes literature 0.10, genetic association 0.00, somatic mutation 0.92).
In plain words · GOLGA5 (Golgin subfamily A member 5) is a gene. The public catalogues list it as a fusion partner, and the evidence so far is association rather than a proven role.
GOLGA5 (Golgin subfamily A member 5) is a gene. The public catalogues list it as a fusion partner, and the evidence so far is association rather than a proven role.
Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons.
No product in this corpus aims at GOLGA5 yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
First described 1989. Earliest sequence paper UniProt cites for the protein: Ishizaka et al, Oncogene, 1989, "Activation of the ret-II oncogene without a sequence encoding a transmembrane domain and transforming activity of two ret-II oncogene products differing in carboxy-termini due to alternative splicing". Source.
Sources: HGNC HGNC:4428 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt Q8TBA6 (protein name, function text, keywords and locations (REST API)); Open Targets ENSG00000066455 (association with cancer (MONDO_0004992) 0.56; (GraphQL API, CC0))
Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport. Location: Golgi apparatus membrane (UniProt). Locus 14q32.12 (HGNC).
Query for this target: (TITLE:"GOLGA5" OR ABSTRACT:"GOLGA5" OR TITLE:"golgin A5" OR ABSTRACT:"golgin A5" OR TITLE:"Golgin subfamily A member 5" OR ABSTRACT:"Golgin subfamily A member 5" OR TITLE:"ret-II" OR ABSTRACT:"ret-II" OR TITLE:"golgin-84" OR ABSTRACT:"golgin-84" OR TITLE:"rfg5" OR ABSTRACT:"rfg5") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about GOLGA5, not a curated reading list.