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GDF7 (Growth/differentiation factor 7) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
May play an active role in the motor area of the primate neocortex.
Open Targets scores its association with cancer at 0.52 (direct and indirect evidence; datatypes literature 0.67, animal model 0.71, genetic association 0.80).
In plain words · GDF7 (Growth/differentiation factor 7) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
GDF7 (Growth/differentiation factor 7) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
May play an active role in the motor area of the primate neocortex. Location: Secreted (UniProt).
No product in this corpus aims at GDF7 yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
First described 2002. Earliest sequence paper UniProt cites for the protein: Guo J.H. et al, 2002. Source.
Sources: HGNC HGNC:4222 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt Q7Z4P5 (protein name, function text, keywords and locations (REST API)); Open Targets ENSG00000143869 (association with cancer (MONDO_0004992) 0.52; (GraphQL API, CC0))
May play an active role in the motor area of the primate neocortex. Location: Secreted (UniProt). Locus 2p24.1 (HGNC).
Query for this target: (TITLE:"GDF7" OR ABSTRACT:"GDF7" OR TITLE:"growth differentiation factor 7" OR ABSTRACT:"growth differentiation factor 7" OR TITLE:"Growth/differentiation factor 7" OR ABSTRACT:"Growth/differentiation factor 7" OR TITLE:"BMP12" OR ABSTRACT:"BMP12") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about GDF7, not a curated reading list.