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FGF9 (Fibroblast growth factor 9) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumours.
Open Targets scores its association with cancer at 0.67 (direct and indirect evidence; datatypes literature 0.98, affected pathway 0.99, animal model 0.85, genetic association 0.29).
In plain words · FGF9 (Fibroblast growth factor 9) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
FGF9 (Fibroblast growth factor 9) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration.
No product in this corpus aims at FGF9 yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
First described 1993. Earliest sequence paper UniProt cites for the protein: Miyamoto et al, Mol. Cell. Biol, 1993, "Molecular cloning of a novel cytokine cDNA encoding the ninth member of the fibroblast growth factor family, which has a unique secretion property". Source.
Sources: HGNC HGNC:3687 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt P31371 (protein name, function text, keywords and locations (REST API)); Open Targets ENSG00000102678 (association with cancer (MONDO_0004992) 0.67; (GraphQL API, CC0))
Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumours. Location: Secreted (UniProt). Locus 13q12.11 (HGNC).
Query for this target: (TITLE:"FGF9" OR ABSTRACT:"FGF9" OR TITLE:"fibroblast growth factor 9" OR ABSTRACT:"fibroblast growth factor 9" OR TITLE:"Fibroblast growth factor 9" OR ABSTRACT:"Fibroblast growth factor 9") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about FGF9, not a curated reading list.