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FGF6 (Fibroblast growth factor 6) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration.
Open Targets scores its association with cancer at 0.61 (direct and indirect evidence; datatypes literature 0.33, affected pathway 0.98).
In plain words · FGF6 (Fibroblast growth factor 6) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
FGF6 (Fibroblast growth factor 6) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration. Location: Secreted, extracellular space (UniProt).
No product in this corpus aims at FGF6 yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
First described 1989. Earliest sequence paper UniProt cites for the protein: Marics et al, Oncogene, 1989, "Characterization of the HST-related FGF.6 gene, a new member of the fibroblast growth factor gene family". Source.
Sources: HGNC HGNC:3684 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt P10767 (protein name, function text, keywords and locations (REST API)); Open Targets ENSG00000111241 (association with cancer (MONDO_0004992) 0.61; (GraphQL API, CC0))
Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration. Location: Secreted, extracellular space (UniProt). Locus 12p13.32 (HGNC).
Query for this target: (TITLE:"FGF6" OR ABSTRACT:"FGF6" OR TITLE:"fibroblast growth factor 6" OR ABSTRACT:"fibroblast growth factor 6" OR TITLE:"Fibroblast growth factor 6" OR ABSTRACT:"Fibroblast growth factor 6") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about FGF6, not a curated reading list.