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FGF20 (Fibroblast growth factor 20) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
Neurotrophic factor that regulates central nervous development and function.
Open Targets scores its association with cancer at 0.62 (direct and indirect evidence; datatypes literature 0.49, affected pathway 0.98, animal model 0.56, genetic association 0.05).
In plain words · FGF20 (Fibroblast growth factor 20) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
FGF20 (Fibroblast growth factor 20) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
Neurotrophic factor that regulates central nervous development and function. Location: Secreted (UniProt).
No product in this corpus aims at FGF20 yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
First described 2000. Earliest sequence paper UniProt cites for the protein: Kirikoshi et al, Biochem. Biophys. Res. Commun, 2000, "Molecular cloning and characterization of human FGF-20 on chromosome 8p21.3-p22". Source.
Sources: HGNC HGNC:3677 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt Q9NP95 (protein name, function text, keywords and locations (REST API)); Open Targets ENSG00000078579 (association with cancer (MONDO_0004992) 0.62; (GraphQL API, CC0))
Neurotrophic factor that regulates central nervous development and function. Location: Secreted (UniProt). Locus 8p22 (HGNC).
Query for this target: (TITLE:"FGF20" OR ABSTRACT:"FGF20" OR TITLE:"fibroblast growth factor 20" OR ABSTRACT:"fibroblast growth factor 20" OR TITLE:"Fibroblast growth factor 20" OR ABSTRACT:"Fibroblast growth factor 20") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about FGF20, not a curated reading list.