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FGF10 (Fibroblast growth factor 10) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing.
Open Targets scores its association with cancer at 0.76 (direct and indirect evidence; datatypes affected pathway 0.97, literature 0.91, genetic association 0.78, somatic mutation 0.61, animal model 0.90).
In plain words · FGF10 (Fibroblast growth factor 10) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
FGF10 (Fibroblast growth factor 10) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis.
No product in this corpus aims at FGF10 yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
First described 1997. Earliest sequence paper UniProt cites for the protein: Emoto et al, J. Biol. Chem, 1997, "Structure and expression of human fibroblast growth factor-10". Source.
Sources: HGNC HGNC:3666 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt O15520 (protein name, function text, keywords and locations (REST API)); Open Targets ENSG00000070193 (association with cancer (MONDO_0004992) 0.76; (GraphQL API, CC0))
Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing. Location: Secreted (UniProt). Locus 5p12 (HGNC).
Query for this target: (TITLE:"FGF10" OR ABSTRACT:"FGF10" OR TITLE:"fibroblast growth factor 10" OR ABSTRACT:"fibroblast growth factor 10" OR TITLE:"Fibroblast growth factor 10" OR ABSTRACT:"Fibroblast growth factor 10") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about FGF10, not a curated reading list.