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FAM131B (family with sequence similarity 131 member B) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
UniProt has no function text for Q86XD5; HGNC names it "family with sequence similarity 131 member B".
Open Targets scores its association with cancer at 0.62 (direct and indirect evidence; datatypes literature 0.12, affected pathway 0.89, genetic association 0.00, somatic mutation 0.49).
In plain words · FAM131B (family with sequence similarity 131 member B) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
FAM131B (family with sequence similarity 131 member B) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
UniProt has no function text for Q86XD5; HGNC names it "family with sequence similarity 131 member B". Locus 7q34 (HGNC).
No product in this corpus aims at FAM131B yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
First described 2003. Earliest sequence paper UniProt cites for the protein: Hillier L.W. et al, Nature, 2003, "The DNA sequence of human chromosome 7". Source.
Sources: HGNC HGNC:22202 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt Q86XD5 (protein name, function text, keywords and locations (REST API)); Open Targets ENSG00000159784 (association with cancer (MONDO_0004992) 0.62; (GraphQL API, CC0))
UniProt has no function text for Q86XD5; HGNC names it "family with sequence similarity 131 member B". Locus 7q34 (HGNC).
Query for this target: (TITLE:"FAM131B" OR ABSTRACT:"FAM131B" OR TITLE:"family with sequence similarity 131 member B" OR ABSTRACT:"family with sequence similarity 131 member B" OR TITLE:"KIAA0773" OR ABSTRACT:"KIAA0773") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about FAM131B, not a curated reading list.