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FAM114A2 (family with sequence similarity 114 member A2) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
UniProt has no function text for Q9NRY5; HGNC names it "family with sequence similarity 114 member A2".
Open Targets scores its association with cancer at 0.55 (direct and indirect evidence; datatypes literature 0.12, affected pathway 0.89, genetic association 0.03).
In plain words · FAM114A2 (family with sequence similarity 114 member A2) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
FAM114A2 (family with sequence similarity 114 member A2) is a gene. In the public catalogues the evidence so far is association rather than a proven role.
UniProt has no function text for Q9NRY5; HGNC names it "family with sequence similarity 114 member A2". Locus 5q33.2 (HGNC).
No product in this corpus aims at FAM114A2 yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
First described 2000. Earliest sequence paper UniProt cites for the protein: Boultwood et al, Genomics, 2000, "Transcription mapping of the 5q- syndrome critical region: cloning of two novel genes and sequencing, expression, and mapping of a further six novel cDNAs". Source.
Sources: HGNC HGNC:1333 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt Q9NRY5 (protein name, function text, keywords and locations (REST API)); Open Targets ENSG00000055147 (association with cancer (MONDO_0004992) 0.55; (GraphQL API, CC0))
UniProt has no function text for Q9NRY5; HGNC names it "family with sequence similarity 114 member A2". Locus 5q33.2 (HGNC).
Query for this target: (TITLE:"FAM114A2" OR ABSTRACT:"FAM114A2" OR TITLE:"family with sequence similarity 114 member A2" OR ABSTRACT:"family with sequence similarity 114 member A2" OR TITLE:"133K02" OR ABSTRACT:"133K02" OR TITLE:"C5orf3" OR ABSTRACT:"C5orf3") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about FAM114A2, not a curated reading list.