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Advanced oesophageal or Siewert type 1 junctional cancer, first line
| Drug | Dose | Route | Days | Note |
|---|---|---|---|---|
Pembrolizumab Monoclonal antibody (anti-PD-1) | 200 mg | IV | D1 | or 400 mg every 6 weeks |
Cisplatin Cytotoxic chemotherapy (platinum) | 80 mg/m² | IV | D1 | |
Fluorouracil infusion Fluoropyrimidine antimetabolite | 800 mg/m² per day | IV | D1-5 (120 h infusion) |
Reference doses for a typical adult from the cited protocol or label. Doses are adjusted for renal and hepatic function, age, performance status and prior toxicity, and institutional protocols vary. Verify against the current label and your local protocol before treating. Not medical advice.