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Pathologists from around the world agreed on what to call the mucinous tumours of the appendix and the jelly-like peritoneal disease they cause, replacing a tangle of older names with low-grade appendiceal mucinous neoplasm, high-grade neoplasm and adenocarcinoma.
Modified Delphi consensus of the Peritoneal Surface Oncology Group International defining terminology for appendiceal mucinous neoplasms (low-grade appendiceal mucinous neoplasm or LAMN, high-grade appendiceal mucinous neoplasm, and mucinous adenocarcinoma with well, moderately or poorly differentiated grades, the last including signet ring cells) and for pseudomyxoma peritonei (acellular mucin, low-grade, high-grade, and high-grade with signet ring cells).
The scheme was adopted by the WHO 2019 digestive classification and underpins prognosis and the decision to offer cytoreductive surgery with HIPEC.
Whether an appendiceal tumour is called LAMN or adenocarcinoma, and whether peritoneal disease is graded low or high, decides prognosis and treatment; this paper set those names.
Shares Low-grade appendiceal mucinous neoplasm and pseudomyxoma peritonei, Appendiceal adenocarcinoma (mucinous and non-mucinous, including signet ring cell).
Shares Low-grade appendiceal mucinous neoplasm and pseudomyxoma peritonei, Appendiceal adenocarcinoma (mucinous and non-mucinous, including signet ring cell).
Shares Low-grade appendiceal mucinous neoplasm and pseudomyxoma peritonei, Appendiceal adenocarcinoma (mucinous and non-mucinous, including signet ring cell).
Shares Low-grade appendiceal mucinous neoplasm and pseudomyxoma peritonei, Appendiceal adenocarcinoma (mucinous and non-mucinous, including signet ring cell).
Shares Low-grade appendiceal mucinous neoplasm and pseudomyxoma peritonei, Appendiceal adenocarcinoma (mucinous and non-mucinous, including signet ring cell).
Shares Low-grade appendiceal mucinous neoplasm and pseudomyxoma peritonei, Appendiceal adenocarcinoma (mucinous and non-mucinous, including signet ring cell).
Shares Low-grade appendiceal mucinous neoplasm and pseudomyxoma peritonei, Appendiceal adenocarcinoma (mucinous and non-mucinous, including signet ring cell).