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The FIGO Oncology Committee's system that combines an anatomical stage with a prognostic score to split gestational trophoblastic neoplasia into low-risk disease, cured with a single drug, and high-risk disease needing combination chemotherapy.
Report of the FIGO Oncology Committee setting out the FIGO 2000 classification of gestational trophoblastic neoplasia: anatomical stages I to IV (uterus, pelvis and adnexa, lungs, other metastases) combined with the modified WHO prognostic scoring system based on age, antecedent pregnancy, interval, hCG level, tumour size, site and number of metastases and prior failed chemotherapy.
A score of 6 or less defines low-risk disease, treated with single-agent methotrexate or dactinomycin, and 7 or more high-risk disease, treated with multi-agent regimens such as EMA/CO. The system replaced several competing schemes and remains in use.
Whether a woman with GTN receives one drug or several rests on this scoring system, which is why OnCo has separate low-risk and high-risk pages.
Shares Low-risk gestational trophoblastic neoplasia (FIGO score 0 to 6), High-risk gestational trophoblastic neoplasia (FIGO score 7 or more, including ultra-high-risk).
Shares Low-risk gestational trophoblastic neoplasia (FIGO score 0 to 6), High-risk gestational trophoblastic neoplasia (FIGO score 7 or more, including ultra-high-risk).
Shares Low-risk gestational trophoblastic neoplasia (FIGO score 0 to 6), High-risk gestational trophoblastic neoplasia (FIGO score 7 or more, including ultra-high-risk).
Shares Low-risk gestational trophoblastic neoplasia (FIGO score 0 to 6), High-risk gestational trophoblastic neoplasia (FIGO score 7 or more, including ultra-high-risk).
Shares Low-risk gestational trophoblastic neoplasia (FIGO score 0 to 6), High-risk gestational trophoblastic neoplasia (FIGO score 7 or more, including ultra-high-risk).
Shares Low-risk gestational trophoblastic neoplasia (FIGO score 0 to 6), High-risk gestational trophoblastic neoplasia (FIGO score 7 or more, including ultra-high-risk).
Shares Low-risk gestational trophoblastic neoplasia (FIGO score 0 to 6), High-risk gestational trophoblastic neoplasia (FIGO score 7 or more, including ultra-high-risk).