The 30-question form that lets cancer trials measure how patients feel and function, tested first in lung cancer patients across 13 countries and now used in thousands of studies.
Aaronson and the EORTC Study Group on Quality of Life designed a core questionnaire for use in international cancer trials and tested it in 305 patients with non-resectable lung cancer in 13 countries before and during treatment. The QLQ-C30 covers five functioning scales (physical, role, cognitive, emotional and social), symptom scales for fatigue, pain and nausea and vomiting, single items for other common symptoms and financial impact, and a global health and quality of life scale. Its scales showed acceptable reliability, distinguished patients by performance status and weight loss, and changed with clinical status over time.
The QLQ-C30 made patient-reported quality of life a standard trial endpoint and is the instrument behind many of the quality of life claims on drug labels and in health technology assessments. Cancer-specific modules were later added on top of the core questionnaire.
Shares Quality of life and patient-reported outcomes (QoL, PRO), Quality of life.
Shares Quality of life and patient-reported outcomes (QoL, PRO), Non-small-cell lung cancer.