Loading
institutionsInstitution
Weizmann Institute of Science
Israel's basic research institute, whose HER receptor, p53, single-cell immunology and microbiome discoveries have shaped cancer biology.
Also called: Weizmann InstituteMoross Integrated Cancer Center
Overview
Founded in 1934 as the Daniel Sieff Institute, the Weizmann Institute of Science created the Moross Integrated Cancer Center in 2016 to link its cancer groups with clinical partners. Yosef Yarden's work on ErbB/HER receptor signalling and antibody combinations, Moshe Oren and Varda Rotter's on p53, Ido Amit's single-cell immunology of tumour myeloid cells, Eran Elinav's microbiome studies and Yardena Samuels's neoantigen discovery in melanoma are widely cited, and Michael Sela's group's early work on combining anti-EGFR antibodies with chemotherapy underpinned patents relevant to cetuximab. The institute's Yeda technology transfer arm has licensed numerous cancer diagnostics and therapeutics, and its scientists collaborate with Sheba, Rambam and international centres.
Location
Rehovot, IL
Type
research institute
Website
Newsweek 2026 oncology rank
Not in top 300 listing used
OnCo score
#126 · 36 points (0 Newsweek + 0 NCI + 36 from 18 linked objects) · ranking
Research output
From OpenAlex, oncology works in the last five years (2022 to 2026, current year in progress); counted on 2026-09-17.
Matched to Weizmann Institute of Science, including child institutions. 183 works · 3,727 citations · 70% open access · 4% clinical trials · 3% reviews.
Oncology works per year
252022
412023
372024
342025
462026
Most works
- Moshe Oren22 works
- Nishanth Belugali Nataraj16 works
- Simone Borgoni13 works
- Yael Aylon12 works
- Ruth Scherz‐Shouval12 works
- Eyal David11 works
- Yosef Yarden11 works
- Ido Amit11 works
- Itay Tirosh10 works
- Angelika Wörner10 works
Most cited
- Moross Integrated Cancer Center
- HER receptor and antibody biology
- p53 biology
- Single-cell immunology
- Microbiome and cancer
Alon Chen
President
NeuroscienceStress biologyResearch leadership
Neuroscientist who has been President of the Weizmann Institute of Science since 2019, leading one of the world's foremost basic research institutes, including its cancer research programmes.
Moshe Oren
Professor, Department of Molecular Cell Biology, Weizmann Institute of Science
p53 biologyMutant p53 gain of functionTumour suppression
Cloned p53 and then spent a career on what it does. The field's first reading of his own 1984 result, that p53 was an oncogene, turned out to be wrong, and the correction is the better story.
Yardena Samuels
Professor, Department of Molecular Cell Biology, Weizmann Institute of Science
Melanoma genomicsNeoantigens and immunopeptidomicsCancer gene discovery
She found that PIK3CA is one of the most frequently mutated genes in human cancer, then spent the next twenty years working out which of a melanoma's mutations the immune system can actually see.
Yosef Yarden
Professor, Department of Immunology and Regenerative Biology, Weizmann Institute of Science
ErbB/HER receptor signallingEGFR biologyAntibody combinations
One of the people who worked out what the HER family of receptors does and how antibodies against them behave, including why combining two antibodies against the same receptor works better than either alone.
Zelig Eshhar
Immunologist; professor emeritus, Weizmann Institute of Science, latterly Immunology Laboratory, Tel Aviv Sourasky Medical Center
Cancer immunologyChimeric antigen receptorsAdoptive cell therapy
The immunologist who, in 1989, first gave a T cell an antibody's aim. Every CAR-T product on the market descends from that experiment.
Similar pages
- PersonAaron Ciechanover
Shares Technion, Israel Institute of Technology, Rambam Health Care Campus.
- IdeaShared splice-derived neoantigens as off-the-shelf vaccine targets
Shares Proteomics & phosphoproteomics, Neoantigen, Acute myeloid leukaemia, Melanoma.
- InstitutionTel Aviv Sourasky Medical Center
Shares Zelig Eshhar, Sheba Medical Center, Colorectal cancer.
- InstitutionMax Delbrück Center for Molecular Medicine
Shares CRISPR functional genomics, Single-cell & spatial profiling, Melanoma, Colorectal cancer.
- CompanyElucidate Bio
Shares Proteomics & phosphoproteomics, Single-cell & spatial profiling.
- InstitutionTel Aviv University
Shares Zelig Eshhar, Sheba Medical Center.
- IdeaFind the parts of a tumour the drug never reaches
Shares Proteomics & phosphoproteomics, Single-cell & spatial profiling.
- InstitutionWellcome Sanger Institute
Shares CRISPR functional genomics, Single-cell & spatial profiling, Melanoma, Colorectal cancer.