The Dutch university cancer centre that invented the MR-linac and sits at the heart of the Utrecht organoid and Oncode ecosystem.
UMC Utrecht's radiotherapy department under Jan Lagendijk and Bas Raaymakers conceived and built the first integrated MRI-guided linear accelerator, commercialised by Elekta as Unity and used to treat the first patients in Utrecht in 2017. The Cancer Center works with the neighbouring Hubrecht Institute, where Hans Clevers's group grew the first adult stem cell-derived organoids, and with the Princess Máxima Center for paediatric oncology on the same campus; Utrecht is also the seat of the Dutch Oncode Institute. Clinical strengths include image-guided and adaptive radiotherapy, head and neck and gastrointestinal oncology, haematology and a phase 1 unit, and the centre holds OECI accreditation. Patients access MR-guided radiotherapy trials, organoid-guided drug testing studies and molecular tumour boards.
From OpenAlex, oncology works in the last five years (2022 to 2026, current year in progress); counted on 2026-09-17.
Matched to University Medical Center Utrecht, including child institutions. 1,422 works · 20,323 citations · 87% open access · 12% clinical trials · 3% reviews.
Physicist who invented the MR-linac, letting radiotherapy see and adapt to the tumour in real time.
Utrecht haematologist and immunotherapy researcher on the daily board of UMC Utrecht's cancer programme, known for gamma-delta T cell receptor-engineered cell therapies.
Genome biologist who chairs UMC Utrecht's Strategic Program Cancer, the umbrella for more than 800 cancer researchers in Utrecht.
Shares Functional (ex vivo) drug testing, Patient-derived organoids, Lab models that fail to predict what happens in patients, SBRT / SABR (stereotactic radiotherapy).
Shares Netherlands Cancer Institute (NKI-AvL), Functional (ex vivo) drug testing, Patient-derived organoids, Lab models that fail to predict what happens in patients.
Shares Elekta, MR-guided adaptive radiotherapy, SBRT / SABR (stereotactic radiotherapy), IMRT / IGRT (modern external beam).
Shares Functional (ex vivo) drug testing, Lab models that fail to predict what happens in patients, Pancreatic ductal adenocarcinoma, Colorectal cancer.
Shares Functional (ex vivo) drug testing, Patient-derived organoids, Lab models that fail to predict what happens in patients, Colorectal cancer.
Shares Sato 2009: single Lgr5 stem cells build crypt-villus organoids, Functional (ex vivo) drug testing, Patient-derived organoids.
Shares Elekta, SBRT / SABR (stereotactic radiotherapy), Head and neck squamous cell carcinoma, IMRT / IGRT (modern external beam).
Shares Functional (ex vivo) drug testing, Patient-derived organoids, Lab models that fail to predict what happens in patients, Pancreatic ductal adenocarcinoma.
Open-source projects that this organisation maintains, from OnCo's own catalogue: licence and last activity as the repository reported them on the day of the fetch. Listing is not endorsement; check the licence before reuse and the validation before clinical use.
A Bioconductor package for characterising mutational patterns and signatures in base substitutions, indels and structural variants.
Classifies central nervous system tumours within the operation from sparse nanopore methylation data, so the surgeon can adapt the resection.