Loading
Thousands of old radium sources sit in hospital and industrial storage. They are exactly the raw material needed to make actinium-225, the scarcest cancer isotope.
Actinium-225 supply from thorium-229 generators (the legacy US and Russian stockpiles) is limited to tens of curies a year, far short of projected demand for alpha radioligand therapy. Accelerator routes (radium-226 irradiated in cyclotrons, linacs or via spallation at TRIUMF) scale with radium feedstock. Radium-226 exists in large quantities in disused brachytherapy sources, industrial gauges and uranium mill tailings, currently classed as waste and expensive to store. The proposal is a coordinated recovery, purification and target-fabrication programme run with the IAEA and national nuclear agencies, offering source holders free disposal in exchange for the material.
Shares Actinium-225 DOTATATE, Actinium-225 PSMA agents, Targeted alpha therapy, Radioligand therapy (beta emitters).
Shares Orano Med, Targeted alpha therapy, Manufacturing cost and time for living and radioactive medicines.
Shares TerraPower Isotopes, Orano Med, Actinium-225 DOTATATE, Actinium-225 PSMA agents.
Shares Targeted alpha therapy, Manufacturing cost and time for living and radioactive medicines, Radioligand therapy (beta emitters).
Shares TerraPower Isotopes, Orano Med, Actinium-225 DOTATATE, Actinium-225 PSMA agents.
Shares TerraPower Isotopes, Targeted alpha therapy, Radioligand therapy (beta emitters).