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People with cirrhosis are meant to have ultrasound scans twice a year, but most do not. A blood test done with their routine liver bloods could catch liver cancer earlier.
GALAD and methylation or protein panels show sensitivity above ultrasound for early hepatocellular carcinoma, while adherence to ultrasound surveillance is under 30% in most reported settings. Propose a randomised trial of blood-based surveillance (MRI for positives) versus ultrasound, with early-stage detection and adherence as endpoints.
Shares Early detection of cancer, The hardest cancers are found late.
Shares Early detection of cancer, The hardest cancers are found late.
Shares Early detection of cancer, The hardest cancers are found late, Liquid biopsy (ctDNA).
Shares Early detection of cancer, MRI, The hardest cancers are found late, Liquid biopsy (ctDNA).
Shares Early detection of cancer, The hardest cancers are found late.
Shares Early detection of cancer, The hardest cancers are found late, Liquid biopsy (ctDNA).
Shares Early detection of cancer, The hardest cancers are found late.
Shares Early detection of cancer, The hardest cancers are found late.