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Ultra-fast FLASH radiotherapy and proton beams may spare healthy tissue dramatically, but the machines cost tens of millions. Engineer versions that any hospital can afford.
FLASH radiotherapy (dose delivered in under a second) reduces normal tissue toxicity in animal models with preserved tumour control and has entered early human trials; proton therapy spares normal tissue by physics but costs an order of magnitude more than photon systems. Compact accelerator concepts (very-high-energy electrons, laser-driven and superconducting compact proton sources) could lower cost. The proposal is a focused engineering programme, with milestone funding, to deliver a compact system capable of FLASH-rate delivery at a capital cost comparable to a conventional linac, paired with the clinical trials needed to establish the FLASH effect in humans.
Shares IBA (Ion Beam Applications), FLASH radiotherapy, Varian (Siemens Healthineers), Surgery and radiotherapy cure most, get least.
Shares Mevion Medical Systems, IBA (Ion Beam Applications), Varian (Siemens Healthineers), Proton therapy.
Shares Varian (Siemens Healthineers), Surgery and radiotherapy cure most, get least, Proton therapy, Toxicity and quality of life are undervalued.
Shares Global cancer surgery: delivering safe, affordable, and timely cancer surgery, Varian (Siemens Healthineers), Surgery and radiotherapy cure most, get least.
Shares Mevion Medical Systems, Proton therapy.
Shares Mevion Medical Systems, IBA (Ion Beam Applications), Varian (Siemens Healthineers), Surgery and radiotherapy cure most, get least.
Shares Mevion Medical Systems, IBA (Ion Beam Applications), Surgery and radiotherapy cure most, get least, Proton therapy.
Shares FLASH radiotherapy, Proton therapy.