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Knowledge about how cancers become resistant is scattered across thousands of papers and company files. Pooling it into one structured, public resource would let anyone see the pattern.
A curated atlas keyed by drug, target, tumour type and prior therapy, recording observed resistance mechanisms with frequencies, sample sizes and evidence grade, populated from published series, trial correlative data and, ideally, industry-contributed data under a common schema. Analogous resources transformed infectious disease (antimicrobial resistance surveillance) and pharmacogenomics.
Shares Drug resistance (primary and acquired), Data silos, Acquired resistance to every therapy.
Shares Drug resistance (primary and acquired), Data silos, Acquired resistance to every therapy.
Shares Drug resistance (primary and acquired), Acquired resistance to every therapy.
Shares Drug resistance (primary and acquired), Acquired resistance to every therapy.
Shares Drug resistance (primary and acquired), Acquired resistance to every therapy.
Shares Foundation Medicine (Roche), Data silos.