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Quemliclustat is an experimental investigational agent whose form is not stated in the registry from Arcus Biosciences in phase 3 trials for pancreatic ductal adenocarcinoma and non-small-cell lung cancer, with its target not yet stated publicly.
Quemliclustat is an investigational agent whose form is not stated in the registry developed by Arcus Biosciences and Gilead Sciences. The sponsor describes its target as adenosine axis, which OnCo does not yet have a target page for. It is the investigational product in 3 recruiting or active industry-led phase 2 and phase 3 interventional cancer trials, including the phase 3 study NCT06608927 (Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma), in pancreatic ductal adenocarcinoma and non-small-cell lung cancer. The largest, NCT06608927, plans to enrol 610 participants with primary completion expected 2030-11-30. Status reflects the highest phase registered on ClinicalTrials.gov; no efficacy results are recorded here.
Ball-and-stick model from PubChem 2D record (no 3D conformer available). PubChem record
Mechanism not stated in the ClinicalTrials.gov record or on the sponsor's pipeline page.
1.Quemliclustat slips into a pocket on its target.
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Query for this drug: (TITLE:"Quemliclustat" OR ABSTRACT:"Quemliclustat") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Quemliclustat, not a curated reading list.
Shares A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies, Study With Various Immunotherapy Treatments in Participants With Lung Cancer, Arcus Biosciences, Gilead Sciences (incl. Kite) and the tag pipeline.
Shares A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies, Study With Various Immunotherapy Treatments in Participants With Lung Cancer, Arcus Biosciences and the tag pipeline.
Shares Pancreatic ductal adenocarcinoma, Non-small-cell lung cancer and the tag pipeline.
Shares Gilead Sciences (incl. Kite), Non-small-cell lung cancer and the tag pipeline.
Shares Pancreatic ductal adenocarcinoma, Non-small-cell lung cancer and the tag pipeline.
Shares Pancreatic ductal adenocarcinoma, Non-small-cell lung cancer and the tag pipeline.
Shares Pancreatic ductal adenocarcinoma, Non-small-cell lung cancer and the tag pipeline.
Shares Pancreatic ductal adenocarcinoma, Non-small-cell lung cancer and the tag pipeline.