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Peluntamig is an experimental bispecific antibody from Phanes Therapeutics in phase 2 trials for non-small-cell lung cancer and neuroendocrine tumours, aimed at CD47 and DLL3.
Peluntamig (PT217) is a bispecific antibody developed by Phanes Therapeutics. Its targets are CD47 and DLL3. ClinicalTrials.gov describes the intervention as: A bispecific antibody (bsAb) against DLL3 and CD47. It is the investigational product in 1 recruiting or active industry-led phase 2 and phase 3 interventional cancer trial, in non-small-cell lung cancer and neuroendocrine tumours. The largest, NCT05652686, plans to enrol 203 participants with primary completion expected 2027-12. Status reflects the highest phase registered on ClinicalTrials.gov; no efficacy results are recorded here.
1.One arm of Peluntamig binds CD47 on the cancer cell.
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Query for this drug: (TITLE:"Peluntamig" OR ABSTRACT:"Peluntamig" OR TITLE:"PT217" OR ABSTRACT:"PT217" OR TITLE:"Peluntamig PT217" OR ABSTRACT:"Peluntamig PT217") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Peluntamig, not a curated reading list.
Shares Obrixtamig, Extrapulmonary neuroendocrine carcinoma, Neuroendocrine tumours and the tag pipeline.
Shares Obrixtamig, Extrapulmonary neuroendocrine carcinoma, Neuroendocrine tumours and the tag pipeline.
Shares Phanes Therapeutics, CD47 and the tag pipeline.
Shares Phanes Therapeutics, Non-small-cell lung cancer and the tag pipeline.
Shares Obrixtamig, Extrapulmonary neuroendocrine carcinoma, Neuroendocrine tumours, Non-small-cell lung cancer and the tag pipeline.
Shares DLL3, Non-small-cell lung cancer and the tag pipeline.
Shares Neuroendocrine tumours, Non-small-cell lung cancer and the tag pipeline.
Shares DLL3 and the tag pipeline.