LEAH Labs makes CAR-T cell therapy for dogs with lymphoma, using virus-free gene editing to bring the cost of a dose down to hundreds of dollars.
LEAH Labs (LifEngine Animal Health Laboratories) is developing CAR-T cell therapy for dogs with B-cell lymphoma, the naturally occurring counterpart of human non-Hodgkin lymphoma, using a non-viral gene-editing approach that the company says brings manufacturing cost to roughly $500 per dose. Its YC profile reports remissions in dogs with late-stage lymphoma. Veterinary cell therapies are regulated by the USDA rather than the FDA, which the company uses to iterate faster; the stated long-term aim is to carry the platform into human oncology.
Shares Y Combinator and the tags veterinary, comparative-oncology.
Shares Y Combinator and the tags veterinary, comparative-oncology.
Shares CD20, CAR-T cell therapy, Diffuse large B-cell lymphoma.
Shares Y Combinator, CAR-T cell therapy.
Shares CD20, Diffuse large B-cell lymphoma.
Shares CD20, CAR-T cell therapy, Diffuse large B-cell lymphoma.
Shares CD20, Diffuse large B-cell lymphoma.