HiberCell is a New York biotech working on the biology of dormant, disseminated cancer cells; its yeast beta-glucan immunotherapy imprime PGG, inherited from Biothera, reached late-stage trials with checkpoint inhibitors.
HiberCell, founded in 2019 in New York, develops therapies against cancer dormancy and relapse and acquired Biothera Pharmaceuticals, whose imprime PGG, a yeast-derived beta-glucan that primes innate immune cells, had been tested with pembrolizumab in breast cancer and melanoma. Its PERK inhibitor and other programmes are in early trials, and the Biothera-era phase 3 record sits on ClinicalTrials.gov under the company as lead sponsor.