Oncology CRO with the largest bank of patient-derived xenograft models (TumorGraft), now adding 3D organoid screening and radiopharmaceutical services.
Champions Oncology, based in Hackensack, New Jersey, and listed as CSBR, is an oncology contract research organisation with the largest bank of patient-derived xenograft models, called TumorGraft, now adding three-dimensional organoid screening and radiopharmaceutical services. It holds more than 1,400 clinically annotated PDX models correlated with patient outcomes, runs the TumorGraft3D organoid platform and reported record fiscal 2026 revenue of 59.4 million dollars with positive adjusted EBITDA. OnCo links it to patient-derived xenografts and organoids, to the bottleneck of preclinical models that do not predict people, and to the idea of running the mouse or organoid trial alongside the human trial. Whether annotated PDX banks predict clinical results better than cell lines is the question its business rests on. The PDX technology page carries the evidence.
Shares Run the mouse or organoid trial at the same time as the human trial, Test drugs on the patient's own cancer cells when there is no trial to join, Patient-derived organoids, Lab models that fail to predict what happens in patients.
Shares Multi-laboratory preclinical trials as the standard for go/no-go decisions, Patient-derived xenografts, Lab models that fail to predict what happens in patients.
Shares Test drugs on the patient's own cancer cells when there is no trial to join, Drug discovery roadmap: screening in mice → maps of dependency → designing in silico, Patient-derived organoids, Lab models that fail to predict what happens in patients.
Shares Patient-derived xenografts, Drug discovery roadmap: screening in mice → maps of dependency → designing in silico, Patient-derived organoids, Lab models that fail to predict what happens in patients.
Shares Patient-derived xenografts, Patient-derived organoids, Lab models that fail to predict what happens in patients.
Shares Patient-derived xenografts, Patient-derived organoids, Lab models that fail to predict what happens in patients.
Shares Patient-derived xenografts, Patient-derived organoids, Lab models that fail to predict what happens in patients.
Shares Patient-derived xenografts, Patient-derived organoids, Lab models that fail to predict what happens in patients.