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Cancers
Multisystem Langerhans cell histiocytosis (with or without risk-organ involvement)
Data

Cancers·Multisystem Langerhans cell histiocytosis (with or without risk-organ involvement)

DataMultisystem Langerhans cell histiocytosis (with or without risk-organ involvement)

Back to the Multisystem Langerhans cell histiocytosis hub →26 connected records

Every connected record, the notes, the JSON, Markdown and RDF twins, and where the record came from and when it was checked.

Overview Types and stages Symptoms and diagnosis Treatment Trials and papers Biology and targets Countries and centres Decisions and support Pipeline and open problems Data

Data

Related pages

26

Direct links plus the targets, companies, and technologies of this cancer's products.

Similar pages

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technologies

Allogeneic stem cell transplantation Cytotoxic chemotherapy Histopathology & immunohistochemistry Liquid biopsy (ctDNA)MRI Small-molecule kinase inhibitors Survivorship care and late-effects surveillance Ultrasound

targets

drugs

ApprovedPurine nucleoside analogue

Cladribine · Leustatin / Litak

ApprovedSmall-molecule kinase inhibitor (MEK1/2)

Cobimetinib · Cotellic

ApprovedSmall-molecule kinase inhibitors (BRAF + MEK)

Dabrafenib + trametinib · Tafinlar + Mekinist

ApprovedSmall-molecule kinase inhibitor (BRAF V600)

Vemurafenib · Zelboraf

ApprovedVinca alkaloid (microtubule inhibitor)

Vinblastine · Velban

companies

Eli Lilly (incl. Loxo)Johnson & Johnson Novartis Roche / Genentech

pathways

RAS / RAF / MEK / ERK (MAPK)

terms

BRAF V600E mutation Cytopenias and myelosuppression Late effects and survivorship toxicity

trials

key papers

LCH-III: therapy prolongation improves outcome in multisystem Langerhans cell histiocytosis Recurrent BRAF mutations in Langerhans cell histiocytosis Vemurafenib for refractory multisystem Langerhans cell histiocytosis in children: an international observational study

Machine-readable versions

The same record for scripts and assistants; checked 2026-09-18. Data CC BY-NC 4.0, attribute “Data from OnCo (onco.cc)”.

JSON with neighbours Markdown context RDF Turtle Sections with routes and counts API root

ProvenanceLast edited 2026-09-18 · Jude Gomila · Key papers for the 39 rare-cancer subtype pages · diff · file

Wikipedia

Langerhans cell histiocytosis

Sources & links

LCH-III (Blood 2013)
NCI PDQ Langerhans cell histiocytosis
Wikipedia

subtype-page paediatric

Data

JSON ·

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Machine-readable versions of Multisystem Langerhans cell histiocytosis (with or without risk-organ involvement)

JSON record with neighbours
Markdown context for language models
RDF Turtle for this record (its triples, relations and owl:sameAs; the IRI of this record is https://onco.cc/cancers/lch-multisystem/)
Section plan: the ten sections of this record with routes, anchors and counts
All cancers as JSON
RDF N-Triples for the whole corpus
Search index: id, kind, name, TL;DR and route for every record
OpenAPI 3.1 description
API root and meta.json
llms.txt

MCP server: npx -y onco-mcp, tools search, get_entity, list_kind, ask, context, compare. This record is get_entity or context with id lch-multisystem.

WebMCP tools registered on this page: onco_search, onco_get_entity.