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Cancers
Central nervous system germ cell tumours (germinoma and non-germinomatous)
Data

Cancers·Central nervous system germ cell tumours (germinoma and non-germinomatous)

DataCentral nervous system germ cell tumours (germinoma and non-germinomatous)

Back to the Central nervous system germ cell tumours hub →30 connected records

Every connected record, the notes, the JSON, Markdown and RDF twins, and where the record came from and when it was checked.

Overview Types and stages Symptoms and diagnosis Treatment Trials and papers Biology and targets Countries and centres Decisions and support Pipeline and open problems Data

Data

Related pages

30

Direct links plus the targets, companies, and technologies of this cancer's products.

Similar pages

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technologies

Allogeneic stem cell transplantation Autologous stem cell transplant (high-dose therapy)Cytotoxic chemotherapy IMRT / IGRT (modern external beam)Intravesical therapy (BCG, chemotherapy, devices, gene and viral therapy)MRI Platinum agents Proton therapy Topoisomerase-I inhibitors (and ADC payloads)

targets

KMT2A (MLL) rearrangement

drugs

ApprovedCytotoxic chemotherapy (platinum)

ApprovedCytotoxic chemotherapy (platinum)

Cisplatin · Platinol (generic)

ApprovedTopoisomerase II inhibitor (podophyllotoxin derivative)

Etoposide · VePesid / Etopophos / Toposar

ApprovedCytotoxic chemotherapy (alkylating agent)

Ifosfamide · Ifex

ApprovedAlkylating agent (ethylenimine)

Thiotepa · Tepadina

companies

Adienne Pharma & Biotech Bristol Myers Squibb Children's Oncology Group (COG)

institutions

SIOP Europe (European Society for Paediatric Oncology)

terms

Alpha-fetoprotein (AFP)Late effects and survivorship toxicity Re-irradiation

trials

ACNS0122 ACNS1123

bottlenecks

Rare and paediatric cancers without markets Survivorship and late effects are neglected

key papers

ACNS1123: response-based reduced radiotherapy for localised CNS non-germinomatous germ cell tumours ACNS1123: response-based reduced-dose whole-ventricular radiotherapy for localised germinoma SIOP CNS GCT 96: outcomes for children and adults with intracranial germinoma treated with radiotherapy alone or chemotherapy plus reduced radiotherapy The 2021 WHO classification of tumours of the central nervous system: a summary

Machine-readable versions

The same record for scripts and assistants; checked 2026-09-17. Data CC BY-NC 4.0, attribute “Data from OnCo (onco.cc)”.

JSON with neighbours Markdown context RDF Turtle Sections with routes and counts API root

ProvenanceLast edited 2026-09-25 · Jude Gomila · One home for cooperative groups · diff · file

Wikipedia

Sources & links

Wikipedia
NCI PDQ: childhood CNS germ cell tumours
SIOP CNS GCT 96 germinoma results (Neuro-Oncology 2013)

subtype-page cns paediatric

Data

JSON ·

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Machine-readable versions of Central nervous system germ cell tumours (germinoma and non-germinomatous)

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