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Trials
Phase 1/2 Study of UI-102 in Selected Advanced Cancers

trialsTrialRecruiting

Phase 1/2 Study of UI-102 in Selected Advanced Cancers

A phase 1/2 trial of UI-102 in advanced solid tumours, run by United Immunity, co., Ltd., now recruiting.

Overview Connected3

Overview

Phase 1/2 Study of UI-102 in Selected Advanced Cancers is a phase 1/2 interventional study registered as NCT07605962 by United Immunity, co., Ltd., with 140 participants planned, started 2026-05-20 and due to reach its primary completion in 2030-03-31. Interventions recorded: UI-102.

Setting

A Phase I/II Open-Label, Dose Escalation, Dose Optimization, and Cohort Expansion Trial to Investigate the Safety, Pharmacokinetics and Pharmacodynamics of UI-102, a Novel Cholesteryl Pullulan (CHP) Nanoparticle-formulated TLR7/8 Agonist in Patients With Selected Locally Advanced and/or Metastatic Solid Tumors

Phase

Phase 1/2

Sponsor

United Immunity, co., Ltd.

Registry

Started

2026-05-20

Enrolled

140 enrolled

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cancers

Metastatic cancer (cancer that has spread)

targets

Toll-like receptor 7 (TLR7)

companies

United Therapeutics

Evidence strength19/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
140 enrolled+11
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Backlink fill · diff · file

Sources & links

ClinicalTrials.gov NCT07605962

Data

JSON ·

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Cancers

Metastatic cancer (cancer that has spread)

Targets

Toll-like receptor 7 (TLR7)

Companies

United Therapeutics

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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