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Trials
Probiotics for Abemaciclib-Induced Abdominal Discomfort.

trialsTrialRecruiting

Probiotics for Abemaciclib-Induced Abdominal Discomfort.

A phase 2 trial of an investigational treatment in advanced solid tumours, run by Leeuwenhoek Laboratories Co. Ltd., now recruiting.

Overview Connected3

Overview

Probiotics for Abemaciclib-Induced Abdominal Discomfort. is a phase 2 interventional study registered as NCT07605728 by Leeuwenhoek Laboratories Co. Ltd., with 80 participants planned, started 2026-05-15 and due to reach its primary completion in 2029-06-30.

Setting

A Randomized, Phase II Study About Probiotics to Alleviate Abemaciclib-induced Abdominal Discomfort Under Standard Anti-diarrhea Drug Loperamide and Changes of Metabolic Factors in Blood.

Phase

Phase 2

Sponsor

Leeuwenhoek Laboratories Co. Ltd.

Registry

Started

2026-05-15 (estimated)

Enrolled

80 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

technologies

CDK4/6 inhibitors

drugs

ApprovedSmall-molecule CDK4/6 inhibitor

Abemaciclib · Verzenio

Evidence strength30/100 · Emerging

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
80 enrolled+10
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 2 corpus-only joins applied · diff · file

Sources & links

ClinicalTrials.gov NCT07605728

Data

JSON ·

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Metastatic cancer (cancer that has spread)

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CDK4/6 inhibitors

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Abemaciclib

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