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Trials
A Study Evaluating the Safety, Pharmacokinetics, and Preliminary Activity of GDC-1261 in Participants With Advanced or Metastatic Prostate Cancer

trialsTrialRecruiting

A Study Evaluating the Safety, Pharmacokinetics, and Preliminary Activity of GDC-1261 in Participants With Advanced or Metastatic Prostate Cancer

A phase 1/2 trial of GDC-1261 in prostate cancer, run by Genentech, Inc., now recruiting.

Overview Connected2

Overview

A Study Evaluating the Safety, Pharmacokinetics, and Preliminary Activity of GDC-1261 in Participants With Advanced or Metastatic Prostate Cancer is a phase 1/2 interventional study registered as NCT07567846 by Genentech, Inc., with 260 participants planned, started 2026-04-29 and due to reach its primary completion in 2027-11-30. Interventions recorded: GDC-1261.

Setting

A Phase I/II Dose-escalation and Expansion Study Evaluating the Safety, Pharmacokinetics, and Preliminary Activity of GDC-1261 in Patients With Advanced or Metastatic Prostate Cancer

Phase

Phase 1/2

Sponsor

Genentech, Inc.

Registry

Started

2026-04-29

Enrolled

260 enrolled

Connected

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cancers

Prostate cancer

companies

Flatiron Health (Roche)

Evidence strength20/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
260 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT07567846

Data

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Flatiron Health (Roche)

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