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Trials
A Clinical Study of Adebrelimab in Combination With SHR-8068 and Chemoradiotherapy as Perioperative Therapy for Locally Advanced Rectal Cancer

trialsTrialRecruiting

A Clinical Study of Adebrelimab in Combination With SHR-8068 and Chemoradiotherapy as Perioperative Therapy for Locally Advanced Rectal Cancer

A phase 2/3 trial of SHR-8068 in colorectal cancer, run by Suzhou Suncadia Biopharmaceuticals Co., Ltd., now recruiting.

Overview Connected4

Overview

A Clinical Study of Adebrelimab in Combination With SHR-8068 and Chemoradiotherapy as Perioperative Therapy for Locally Advanced Rectal Cancer is a phase 2/3 interventional study registered as NCT07454720 by Suzhou Suncadia Biopharmaceuticals Co., Ltd., with 165 participants planned, started 2026-03-23 and due to reach its primary completion in 2032-11. Interventions recorded: Adebrelimab in combination with SHR-8068 and chemotherapy, Adebrelimab combined with chemotherapy, Chemotherapy. Conditions listed: Locally Advanced Resectable Rectal Cancer. No results are recorded here; the registry entry is the source.

Setting

A Randomized, Double-blind, Placebo-controlled, Multicenter Phase II/III Clinical Study of Adebrelimab Combined With SHR-8068 and Chemoradiotherapy as Perioperative Therapy for Locally Advanced Resectable Rectal Cancer

Phase

Phase 2/3

Sponsor

Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Registry

Started

2026-03-23

Enrolled

165 enrolled

Connected

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cancers

Colorectal cancer Rectal cancer

drugs

Phase 3monoclonal antibody (anti-CTLA-4, per the sponsor's pipeline page; form not stated in the registry record)

companies

Jiangsu Hengrui Pharmaceuticals

Evidence strength33/100 · Emerging

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2/3+22
165 enrolled+11
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Link 1,018 registry trials to cancer subtype pages by dri… · diff · file

Sources & links

ClinicalTrials.gov NCT07454720

Data

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Cancers

Colorectal cancer
Rectal cancer

Products

SHR-8068

Companies

Jiangsu Hengrui Pharmaceuticals

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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