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Trials
A Clinical Study of SHR-4394 in Combination With Anti-tumor Therapy in Prostate Cancer

trialsTrialRecruiting

A Clinical Study of SHR-4394 in Combination With Anti-tumor Therapy in Prostate Cancer

A phase 1/2 trial of Rezvilutamide, Tazemetostat in prostate cancer, run by Jiangsu HengRui Medicine Co., Ltd., now recruiting.

Overview Connected4

Overview

A Clinical Study of SHR-4394 in Combination With Anti-tumor Therapy in Prostate Cancer is a phase 1/2 interventional study registered as NCT07407283 by Jiangsu HengRui Medicine Co., Ltd., with 100 participants planned, started 2026-04-08 and due to reach its primary completion in 2027-11. Interventions recorded: SHR-4394, Rezvilutamide, HRS-5041 Tablets, Tazemetostat. Conditions listed: Prostate Cancer. No results are recorded here; the registry entry is the source.

Setting

A Multicenter, Open-label, Phase Ib/II Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of SHR-4394 in Combination With Anti-tumor Therapy in Participants With Prostate Cancer

Phase

Phase 1/2

Sponsor

Jiangsu HengRui Medicine Co., Ltd.

Registry

Started

2026-04-08

Enrolled

100 enrolled

Connected

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Treatment
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cancers

Prostate cancer

drugs

ApprovedOral androgen receptor antagonist

WithdrawnSmall-molecule EZH2 inhibitor

Tazemetostat · Tazverik

companies

Jiangsu Hengrui Pharmaceuticals

Evidence strength23/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
100 enrolled+10
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Header signup, trial wave 5 and Ask weighting · diff · file

Sources & links

ClinicalTrials.gov NCT07407283

Data

JSON ·

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Cancers

Prostate cancer

Products

Rezvilutamide
Tazemetostat

Companies

Jiangsu Hengrui Pharmaceuticals

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