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Trials
A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement

trialsTrialRecruiting

A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement

A phase 2 trial of Lirafugratinib in advanced solid tumours, run by Elevar Therapeutics, now recruiting.

Also called: ReFocus202

Overview Connected3

Overview

A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement is a phase 2 interventional study registered as NCT07359820 by Elevar Therapeutics, with 30 participants planned, started 2026-06-04 and due to reach its primary completion in 2027-09. Interventions recorded: Lirafugratinib.

Setting

A Phase 2, Open-Label, Single-Arm Study of Lirafugratinib in Patients With Previously Treated, Unresectable, Locally Advanced or Metastatic Solid Tumors (Excluding Cholangiocarcinoma) With FGFR2 Fusion or Rearrangement

Phase

Phase 2

Sponsor

Elevar Therapeutics

Registry

Started

2026-06-04

Enrolled

30 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

drugs

ApprovedSmall-molecule FGFR2 inhibitor

Lirafugratinib · Lyrfigtu

companies

Elevar Therapeutics (HLB)

Evidence strength27/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
30 enrolled+7
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · A further 160 trial acronyms added as aliases to registry… · diff · file

Sources & links

ClinicalTrials.gov NCT07359820

Data

JSON ·

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Cancers

Metastatic cancer (cancer that has spread)

Products

Lirafugratinib

Companies

Elevar Therapeutics (HLB)

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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