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Trials
Study of an AAV Mediated Dual-Payload Gene Therapy in Patients With High Grade Glioma

trialsTrialRecruiting

Study of an AAV Mediated Dual-Payload Gene Therapy in Patients With High Grade Glioma

A phase 1/2 trial of TGX-007 in glioma & glioblastoma, run by Trogenix ltd, now recruiting.

Also called: ADePT

Overview Connected2

Overview

Study of an AAV Mediated Dual-Payload Gene Therapy in Patients With High Grade Glioma is a phase 1/2 interventional study registered as NCT07346144 by Trogenix ltd, with 68 participants planned, started 2026-04-21 and due to reach its primary completion in 2030-03. Interventions recorded: TGX-007 and Valaciclovir.

Setting

A Phase I/II Study of an AAV-1 Mediated Dual-Payload Gene Therapy in Patients With High Grade Glioma

Phase

Phase 1/2

Sponsor

Trogenix ltd

Registry

Started

2026-04-21

Enrolled

68 enrolled

Connected

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cancers

Glioma & glioblastoma

companies

TROG Cancer Research

Evidence strength17/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
68 enrolled+9
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-25 · Jude Gomila · One home for cooperative groups · diff · file

Sources & links

ClinicalTrials.gov NCT07346144

Data

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Cancers

Glioma & glioblastoma

Companies

TROG Cancer Research

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