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Trials
CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

trialsTrialRecruiting

CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

A phase 1/2 trial of CR-001 in advanced solid tumours, run by Crescent Biopharma, Inc., now recruiting.

Also called: ASCEND

Overview Connected1

Overview

CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors is a phase 1/2 interventional study registered as NCT07335497 by Crescent Biopharma, Inc., with 290 participants planned, started 2026-02-17 and due to reach its primary completion in 2029-02. Interventions recorded: CR-001.

Setting

A Phase 1/2, Multicenter, Open-label, Dose Escalation and Dose Expansion Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

Phase

Phase 1/2

Sponsor

Crescent Biopharma, Inc.

Registry

Started

2026-02-17

Enrolled

290 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

Evidence strength20/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
290 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Add 115 registry trial acronyms from the CT.gov acronym f… · diff · file

Sources & links

ClinicalTrials.gov NCT07335497

Data

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