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Trials
A Study of QLC5508 Combinations in Patients With Advanced Solid Tumors

trialsTrialRecruiting

A Study of QLC5508 Combinations in Patients With Advanced Solid Tumors

A phase 1/2 trial of QLC5508, QL1706, Carboplatin, Cisplatin, QL2107 and Fluorouracil (5-FU) in advanced solid tumours, run by Qilu Pharmaceutical Co., Ltd., now recruiting.

Overview Connected8

Overview

A Study of QLC5508 Combinations in Patients With Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT07256782 by Qilu Pharmaceutical Co., Ltd., with 444 participants planned, started 2025-10-24 and due to reach its primary completion in 2026-10. Interventions recorded: QLC5508, QL1706, Cisplatin/ Carboplatin, QL2107, Paclitaxel and 5-fluorouracil (5-FU).

Setting

A Phase Ib/II, Open-label, Multi-center Study to Evaluate Safety, Tolerability, Pharmacokinetics and Efficacy of Intravenous Administration of QLC5508 in Combination With Other Anti-tumor Agents in Patients With Advanced Solid Tumors

Phase

Phase 1/2

Sponsor

Qilu Pharmaceutical Co., Ltd.

Registry

Started

2025-10-24

Enrolled

444 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

drugs

ApprovedCytotoxic chemotherapy (platinum)

ApprovedCytotoxic chemotherapy (platinum)

Cisplatin · Platinol (generic)

ApprovedFluoropyrimidine antimetabolite

Fluorouracil (5-FU) · Adrucil / Efudex

Phase 3bifunctional antibody mixture (iparomlimab and tuvonralimab; INN stem -mab)

Phase 3not stated (registered as a drug or biological on ClinicalTrials.gov)

Phase 3ADC

companies

Qilu Pharmaceutical

Evidence strength26/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
444 enrolled+13
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT07256782

Data

JSON ·

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Cancers

Metastatic cancer (cancer that has spread)

Products

QLC5508
QL1706
Carboplatin
Cisplatin
QL2107
Fluorouracil (5-FU)

Companies

Qilu Pharmaceutical

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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