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Trials
A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

trialsTrialRecruiting

A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

A phase 1/2 trial of TAK-188 in advanced solid tumours, run by Takeda, now recruiting.

Overview Connected2

Overview

A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors is a phase 1/2 interventional study registered as NCT07205718 by Takeda, with 223 participants planned, started 2025-11-19 and due to reach its primary completion in 2028-12-26. Interventions recorded: TAK-188.

Setting

An Open-label, Dose Escalation and Expansion, Phase 1/2 Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of TAK- 188, an Anti-CCR8 Antibody-Drug- Conjugate, as a Single Agent in Adult Participants With Locally Advanced or Metastatic Solid Tumors

Phase

Phase 1/2

Sponsor

Takeda

Registry

Started

2025-11-19

Enrolled

223 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

companies

Evidence strength20/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
223 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT07205718

Data

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Metastatic cancer (cancer that has spread)

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