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Trials
A Study of GR1014 Cutaneous Gel for the Prevention of Skin Reactions Caused by Radiation Therapy for Breast Cancer

trialsTrialActive

A Study of GR1014 Cutaneous Gel for the Prevention of Skin Reactions Caused by Radiation Therapy for Breast Cancer

A phase 2 trial of GR1014-CG 2.4% in advanced solid tumours, run by Graegis Pharmaceuticals Ltd, active and no longer recruiting.

Also called: GuARD

Overview Connected1

Overview

A Study of GR1014 Cutaneous Gel for the Prevention of Skin Reactions Caused by Radiation Therapy for Breast Cancer is a phase 2 interventional study registered as NCT07192588 by Graegis Pharmaceuticals Ltd, with 273 participants enrolled, started 2024-07-26 and due to reach its primary completion in 2026-09-30. Interventions recorded: GR1014-CG 2.4%, Vehicle Gel, Radiation Therapy and GR1014-CG 4.7%.

Setting

A Randomised, Double-Blind, Vehicle-Controlled, Multi-Centre, Parallel-Group Study to Investigate the Safety, Tolerability, and Efficacy of GR1014 Cutaneous Gel as a Topical Radioprotector in the Prevention of the Radiodermatitis Occurring With Adjuvant Radiotherapy for Localised Breast Cancer After Lumpectomy

Phase

Phase 2

Sponsor

Graegis Pharmaceuticals Ltd

Registry

Started

2024-07-26

Enrolled

273 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

Evidence strength27/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
273 enrolled+12
No structured primary endpoint0
Result: active0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · A further 160 trial acronyms added as aliases to registry… · diff · file

Sources & links

ClinicalTrials.gov NCT07192588

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