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Trials
Gene Therapy for HER-Positive Cancer (SENTRY-HER2)

trialsTrialRecruiting

Gene Therapy for HER-Positive Cancer (SENTRY-HER2)

A phase 1/2 trial of Dose Level 1, VNX-202 in advanced solid tumours, run by Vironexis Biotherapeutics Inc., now recruiting.

Also called: SENTRY-HER2

Overview Connected3

Overview

Gene Therapy for HER-Positive Cancer (SENTRY-HER2) is a phase 1/2 interventional study registered as NCT07192432 by Vironexis Biotherapeutics Inc., with 27 participants planned, started 2025-11-18 and due to reach its primary completion in 2033-09. Interventions recorded: Dose Level 1, VNX-202, Dose Level 2, VNX-202, Dose Level 3, VNX-202 and Dose Level 4, VNX-202.

Setting

A Phase 1/2, First-in-Human Study of VNX-202 Gene Therapy in Patients With HER2-Positive Cancer

Phase

Phase 1/2

Sponsor

Vironexis Biotherapeutics Inc.

Registry

Started

2025-11-18

Enrolled

27 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

targets

companies

Vironexis Biotherapeutics

Evidence strength15/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
27 enrolled+7
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Trial acronyms for registry records · diff · file

Sources & links

ClinicalTrials.gov NCT07192432

Data

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Cancers

Metastatic cancer (cancer that has spread)

Targets

HER2

Companies

Vironexis Biotherapeutics

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Model panel commentary is coming to this page: machine commentary, not clinical review.

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