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Trials
A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer

trialsTrialRecruiting

A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer

A phase 2 trial of LY3537021 in advanced solid tumours, run by Eli Lilly and Company, now recruiting.

Overview Connected2

Overview

A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer is a phase 2 interventional study registered as NCT07169851 by Eli Lilly and Company, with 204 participants planned, started 2025-11-28 and due to reach its primary completion in 2026-12. Interventions recorded: LY3537021, Placebo, Standard of Care Antiemetic Therapies and Background Chemotherapy.

Setting

A Phase 2, Double-blind, Placebo-Controlled Study to Evaluate LY3537021 for the Treatment of Chemotherapy-Induced Nausea and Vomiting in Adult Participants With Malignant Disease

Phase

Phase 2

Sponsor

Eli Lilly and Company

Registry

Started

2025-11-28

Enrolled

204 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

companies

Eli Lilly (incl. Loxo)

Evidence strength27/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
204 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT07169851

Data

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Cancers

Metastatic cancer (cancer that has spread)

Companies

Eli Lilly (incl. Loxo)

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