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Trials
Study of TLX101-Tx Plus Standard of Care (SoC) Versus SoC Alone for the Treatment of Patients With Recurrent Glioblastoma

trialsTrialRecruiting

Study of TLX101-Tx Plus Standard of Care (SoC) Versus SoC Alone for the Treatment of Patients With Recurrent Glioblastoma

A phase 3 trial of TLX-101-Tx + Lomustine in glioma & glioblastoma, run by Telix Pharmaceuticals (Innovations) Pty Limited, now recruiting.

Also called: IPAX-3

Overview Connected2

Overview

Study of TLX101-Tx Plus Standard of Care (SoC) Versus SoC Alone for the Treatment of Patients With Recurrent Glioblastoma is a phase 3 interventional study registered as NCT07100730 by Telix Pharmaceuticals (Innovations) Pty Limited, with 50 participants planned, started 2025-11-02 and due to reach its primary completion in 2027-07. Interventions recorded: TLX-101-Tx + Lomustine and TLX101-Tx.

Setting

A Global, Multicenter, Prospective, Controlled, Open-Label Pivotal Study of Iodofalan (131I) Solution for Injection (TLX101-Tx) Plus Lomustine Versus Lomustine Alone in Patients With Radiographically Confirmed Recurrent Glioblastoma at First Recurrence (IPAX BrIGHT [IPAX-3])

Phase

Phase 3

Sponsor

Telix Pharmaceuticals (Innovations) Pty Limited

Registry

Started

2025-11-02

Enrolled

50 enrolled

Connected

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cancers

Glioma & glioblastoma

companies

Telix Pharmaceuticals

Evidence strength38/100 · Emerging

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 3+30
50 enrolled+8
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Trial acronyms for registry records · diff · file

Sources & links

ClinicalTrials.gov NCT07100730

Data

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Glioma & glioblastoma

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Telix Pharmaceuticals

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MCP server: npx -y onco-mcp, tools search, get_entity, list_kind, ask, context, compare. This record is get_entity or context with id nct07100730.

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