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Trials
A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer

trialsTrialActive

A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer

A phase 1/2 trial of Disitamab vedotin in advanced solid tumours, run by Pfizer, active and no longer recruiting.

Overview Connected4

Overview

A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer is a phase 1/2 interventional study registered as NCT06966453 by Pfizer, with 74 participants enrolled, started 2025-06-30 and due to reach its primary completion in 2027-10-25. Interventions recorded: Disitamab vedotin.

Setting

A PHASE 1B/2, OPEN-LABEL, MULTICOHORT STUDY OF DISITAMAB VEDOTIN IN ADULTS WITH HER2 EXPRESSING ADVANCED BREAST CANCER

Phase

Phase 1/2

Sponsor

Pfizer

Registry

Started

2025-06-30

Enrolled

74 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

technologies

Antibody-drug conjugate (ADC)

drugs

ApprovedADC

Disitamab vedotin

companies

Pfizer (incl. Seagen)

Evidence strength22/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
74 enrolled+9
No structured primary endpoint0
Result: active0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 2 corpus-only joins applied · diff · file

Sources & links

ClinicalTrials.gov NCT06966453

Data

JSON ·

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Cancers

Metastatic cancer (cancer that has spread)

Technologies

Antibody-drug conjugate (ADC)

Products

Disitamab vedotin

Companies

Pfizer (incl. Seagen)

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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