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Trials
Study of TYK-00540 Tablets in Patients With Advanced Solid Tumors

trialsTrialRecruiting

Study of TYK-00540 Tablets in Patients With Advanced Solid Tumors

A phase 1/2 trial of TYK-00540 in HR-positive / HER2-negative breast cancer, run by TYK Medicines, Inc, now recruiting.

Overview Connected2

Overview

Study of TYK-00540 Tablets in Patients With Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT06950086 by TYK Medicines, Inc, with 180 participants planned, started 2024-01-02 and due to reach its primary completion in 2026-09. Interventions recorded: TYK-00540.

Setting

A Phase I/II Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of the CDK2/4/6 Inhibitor TYK-00540 Tablets in Patients With Advanced Solid Tumors

Phase

Phase 1/2

Sponsor

TYK Medicines, Inc

Registry

Started

2024-01-02

Enrolled

180 enrolled

Connected

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cancers

HR-positive / HER2-negative breast cancer

companies

Evidence strength19/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
180 enrolled+11
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Orphan trials · diff · file

Sources & links

ClinicalTrials.gov NCT06950086

Data

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Cancers

HR-positive / HER2-negative breast cancer

Companies

TYK Medicines

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