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Trials
A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

trialsTrialRecruiting

A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

A phase 1/2 trial of NDI-219216 in advanced solid tumours, run by Nimbus Wadjet, Inc., now recruiting.

Overview Connected3

Overview

A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors. is a phase 1/2 interventional study registered as NCT06898450 by Nimbus Wadjet, Inc., with 134 participants planned, started 2025-03-31 and due to reach its primary completion in 2031-10. Interventions recorded: NDI-219216.

Setting

A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of NDI-219216 in Patients With Advanced Solid Tumors With/Without Microsatellite Instability and/or Deficient Mismatch Repair

Phase

Phase 1/2

Sponsor

Nimbus Wadjet, Inc.

Registry

Started

2025-03-31

Enrolled

134 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

drugs

Phase 2small molecule (structure undisclosed or not yet in PubChem)

companies

Nimbus Therapeutics

Evidence strength19/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
134 enrolled+11
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT06898450

Data

JSON ·

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Cancers

Metastatic cancer (cancer that has spread)

Products

NDI-219216

Companies

Nimbus Therapeutics

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

Machine-readable versions of A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

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MCP server: npx -y onco-mcp, tools search, get_entity, list_kind, ask, context, compare. This record is get_entity or context with id nct06898450.

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