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Trials
Phase 1/2 Study of IMC-R117C in Selected Advanced Cancers

trialsTrialRecruiting

Phase 1/2 Study of IMC-R117C in Selected Advanced Cancers

A phase 1/2 trial of IMC-R117C in advanced solid tumours, run by Immunocore Ltd, now recruiting.

Overview Connected2

Overview

Phase 1/2 Study of IMC-R117C in Selected Advanced Cancers is a phase 1/2 interventional study registered as NCT06840119 by Immunocore Ltd, with 600 participants planned, started 2024-01-10 and due to reach its primary completion in 2026-11-30. Interventions recorded: IMC-R117C, Chemotherapy drug, Kinase inhibitor, Antiangiogenic Agent and Monoclonal antibody.

Setting

A Phase 1/2 First-in-Human Study of the Safety and Efficacy of IMC-R117C (PIWIL1 × CD3 ImmTAC® Bispecific Protein) as a Single Agent and in Combination in HLA-A*02:01-Positive Participants With Selected Advanced PIWIL1-Positive Cancers

Phase

Phase 1/2

Sponsor

Immunocore Ltd

Registry

Started

2024-01-10

Enrolled

600 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

companies

Evidence strength22/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
600 enrolled+14
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT06840119

Data

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Cancers

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MCP server: npx -y onco-mcp, tools search, get_entity, list_kind, ask, context, compare. This record is get_entity or context with id nct06840119.

WebMCP tools registered on this page: onco_search, onco_get_entity.