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Trials
Study of DT-7012 as a Single Agent and in Combination With an Immune Checkpoint Inhibitor in Participants With Advanced Solid Tumors

trialsTrialRecruiting

Study of DT-7012 as a Single Agent and in Combination With an Immune Checkpoint Inhibitor in Participants With Advanced Solid Tumors

A phase 1/2 trial of DT-7012 in advanced solid tumours, run by Domain Therapeutics Australia Pty Ltd, now recruiting.

Also called: DOMISOL

Overview Connected1

Overview

Study of DT-7012 as a Single Agent and in Combination With an Immune Checkpoint Inhibitor in Participants With Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT06819735 by Domain Therapeutics Australia Pty Ltd, with 125 participants planned, started 2025-06-25 and due to reach its primary completion in 2027-09. Interventions recorded: DT-7012 and Immune checkpoint inhibitor.

Setting

A Phase 1/2, Multicentre, Open-label Clinical Trial of DT-7012 as Monotherapy and in Combination With an Immune Checkpoint Inhibitor in Participants With Selected Advanced Solid Tumors (DOMISOL, DOmain_therapeutics Monoclonal antIbody for SOLid Tumors)

Phase

Phase 1/2

Sponsor

Domain Therapeutics Australia Pty Ltd

Registry

Started

2025-06-25

Enrolled

125 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

Evidence strength18/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
125 enrolled+10
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Add 115 registry trial acronyms from the CT.gov acronym f… · diff · file

Sources & links

ClinicalTrials.gov NCT06819735

Data

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